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The establishment of EVISA is funded by the EU through the Fifth Framework Programme (G7RT- CT- 2002- 05112).


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Bioanalysis


 

Status
active
Indexing
Chemical Abstracts; Science Citation Index Expanded (also known as SciSearch®); BIOSIS Previews; BIOSIS Reviews Reports and Meetings; MEDLINE/Index Medicus
Subject

Source type
Journal
ISBN ISSN
1757-6180
E ISSN
1757-6199
First volume
1
Last volume
3+
Publish city
London
Homepage
Description

Reliable data obtained from selective, sensitive and reproducible analysis of a drug and its metabolites in biological samples is a fundamental and crucial part of every successful drug development program. Indeed, the same principles apply to many areas such as forensic science, toxicology and sports doping testing.

The field of bioanalysis has matured significantly from early studies in drug metabolism using simple colorimetry. With the proliferation of sophisticated hyphenated techniques linking advanced separations with mass spectrometry and NMR as detection systems, automation and robotics, today's bioanalyst is well equipped to deal with the modern challenges of analyzing xenobiotics in biological matrices much faster and with a higher level of confidence. Furthermore, bioanalysts are now involved with the discovery, measurement and qualification of pharmacogenomic profiles and biomarkers and, subsequently, the development of diagnostic kits to individualize patient characterization and treatment.

Bioanalysis is a progressive discipline for which the future holds many exciting opportunities to further improve sensitivity, specificity, accuracy, efficiency, assay throughput, data quality, data handling and processing, analysis cost and environmental impact. Standards set by regulatory bodies regarding method development and validation increasingly define the boundaries between speed and quality. Bioanalysis encourages the submission of any forward looking applications, including biosensors, microfluidics, miniaturized analytical devices, and new hyphenated and multi-dimensional techniques.

In today’s highly competitive global drug development arena, it is more important than ever that the modern bioanalytical laboratory is optimized for speed and success.

Bioanalysis provides the busy bioanalyst with a forum for the rapid publication of original research and critical reviews of all the latest relevant and significant developments, including:

  • Analyte extraction and sample preparation
  • Biomarker assays
  • Chromatography and separation sciences
  • Data processing and statistics
  • Diagnostic assays and test kits
  • Drug and metabolite assays
  • Innovative bioanalytical methods
  • Laboratory automation and efficiency
  • Ligand binding assays
  • Mass spectrometry and other key detection methods
  • Method development and validation reports
  • New instrumentation and equipment
  • Pharmacogenomics assays
  • Regulatory and compliance issues

Bioanalysis delivers essential information in concise, at-a-glance article formats. Key advances in the field are reported and analyzed by international experts, providing an authoritative but accessible forum for the modern bioanalyst. A regular Bioanalytical Challenges feature provides practical advice and troubleshooting to laboratory based problems from world renowned experts.

The content is uniquely targeted to those working on the analysis of drugs and metabolites in biological matrices. This is, primarily, bioanalysts working in pharmaceutical research and development, clinical laboratories, clinical toxicologists, forensic toxicologists and sports doping analysts. The articles will also have wide appeal to analytical chemists, mass spectroscopists, chromatographers, pharmacologists, clinical chemists, analytical toxicologists, and those involved with studies of drug metabolism, pharmacokinetics, toxicity, bioequivalence and metabolomics.



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