Matrix assisted laser desorption ionization mass spectrometry (MALDI) is a mass spectrometric technique that is used for the analysis of large biomolecules. Analyte molecules are embedded in an excess matrix of small organic molecules that show a high resonant absorption at the laser wavelength used. The matrix absorbs the laser energy, thus inducing a soft disintegration of the sample-matrix mixture into free (gas phase) matrix and analyte molecules and molecular ions. In general, only molecular ions of the analyte molecules are produced and almost no fragmentation occurs. This makes the method well suited for molecular weight determinations and mixture analysis.

The term "MALDI" was found in the following pages:

Instrument database: Applied Biosystems - QSTAR® XL Hybrid LC/MS/MS System
CSI 2012: XXXVIII Colloqium Spectroscopicum Internationale | EVISA's Agenda of Events
Instrument database: Shimadzu Europe - AXIMA Resonance - MALDI-TOF Mass Spectrometer
CSI XLII: Colloquium Spectroscopicum Internationale XLII | EVISA's Agenda of Events
Instrument database: Agilent Technologies Inc. - 1260 Infinity Micro-scale Purification/Spotting System
Instrument database: Applied Biosystems - 4800 Plus MALDI TOF/TOF™ Analyzer
Instrument database: Shimadzu Corporation - LAMS-50K MALDI-TOF MS
Colloquium Spectroscopicum Internationale (CSI XXXVI) | EVISA's Agenda of Events
Company database: Micromass by Waters
Instrument database: Bruker Daltonics - ultrafleXtreme MALDI TOF-TOF
Instrument database: Bruker Daltonics - esquire6000
Instrument database: Bruker Daltonics - autoflex™ speed MALDI-TOF(/TOF)
Instrument database: Bruker Daltonics - esquire4000
Directory of scientists: H. M. "Skip" Kingston
Instrument database: Shimadzu Europe - AXIMA Performance -MALDI
Instrument database: Bruker Daltonics - microflex MALDI TOF-MS
Instrument database: Kratos Analytical - AXIMA CFR MALDI TOF Mass Spectrometer
Brief summary: Speciation analysis for the study of metallodrugs and their biomolecular interactions | EVISA's News
Instrument database: Bruker Daltonics - micrOTOF - benchtop ESI-TOF MS
Instrument database: Bruker Daltonics - ultraflex II & ultraflex II TOF/TOF