species-specific isotope dilution

Species-specific isotope dilution (sometimes also called speciated isotope dilution) is an isotope dilution technique using a spike compound identical to the compound under investigation but labeled with a specific isotope of the target element. Species-specific ID analysis is only possible for element species well defined in their structure and composition. The equilibration of the spike and the analyte in the sample, attainable in classical IDMS by multiple sequential dissolution and evaporation cycles, cannot be guaranteed to be achieved for species-specific ID analysis of solid samples. If applicable, the method can correct for loss of analyte during sample preparation following the spike addition, incomplete derivatisation yield and for intensity suppression/enhancement during detection.



The term "species-specific isotope dilution" was found in the following pages:

Species-specific isotope dilution analysis has been adopted as an official method under US legislation | EVISA's News
New Reference Material for Hexavalent Chromium in Contaminated Soil | EVISA's News
Chromium speciation in solid matrices | EVISA's News
Standard methods for mercury speciation analysis | EVISA's News
A new quantification strategy for bioimaging by laser ablation - inductively coupled plasma-mass spectrometry based on isotope dilution analysis | EVISA's News
New mass spectrometric method allows fast and comprehensive analyses of metabolites | EVISA's News
Problems to be solved
Speciation Analysis - Striving for Quality | EVISA's News
Directory of scientists: H. M. "Skip" Kingston
Accurate determination of hexavalent chromium in agricultural soil | EVISA's News
Species transformation during speciation analysis | EVISA's News
PLSG Invests $100,000 in Applied Isotope Technologies, Inc., for Development of New Technologies for Environmental and Biological Analyses | EVISA's News
Directory of scientists: Tea Zuliani
Material database: IRMM - Institute for Reference Materials and Measurements - ERM-AE671 CH3(202Hg)Cl in 2 % Ethanol/Water
Directory of scientists: Pablo Rodriguez-Gonzalez
Directory of scientists: G. M. Mizanur Rahman
Problems to be solved in the field of speciation analysis
Double spiking species-specific isotope dilution result calculations simplified | EVISA's News
Directory of scientists: Claudia Swart
Sample preservation for speciation analysis - General recommendations | EVISA's News