ICP-MS

ICP-MS (Inductively Coupled Plasma Mass Spectrometry) is a type of mass spectrometry that is highly sensitive and capable of simultaneous determination of a range of elements at below one part in 1012. It is based on coupling together an inductively coupled plasma as an ion source with a mass spectrometer as a detection system for ions.
 
The ions generated within the plasma at atmospheric pressure are extracted through a series of cones into the vacuum chamber of a mass spectrometer, usually a quadrupole. Other mass analyzers coupled to ICP systems include double focusing magnetic-electric sector systems with both single and multiple collector, as well as time-of-flight (TOF) systems (both with axial and orthogonal accelerators). In any case the ions are separated on the basis of their mass-to-charge ratio and a detector receives an ion signal proportional to the concentration.
 
The concentration of a sample can be determined through calibration with elemental standards (external calibration). Accuracy and precision can be enhanced by using internal standards and rationing the measurements against these. ICP-MS also lends itself to quantitative determinations through isotope dilution analysis, a single point method based on an isotopically enriched standard.
 
 



The term "ICP-MS" was found in the following pages:

New arsenic compounds found in herring | EVISA's News
Instrument database: Glass Expansion - Assist - Syringe-driven sample introduction system
Instrument database: Elemental Scientific Inc. (ESI) - SC-14 Autosampler
Polish selenium supplements not always labeled accurately | EVISA's News
Bromine Speciation in Human Serum | EVISA's News
The Role of Phytochelatins for Metal Detoxification in Animals | EVISA's News
Instrument database: Milestone S.r.l. - UltraClave Microwave Autoclave
Liquid-liquid extraction in speciation analysis | EVISA's News
Instrument database: SII Nano Technology Inc. - SPQ9200ev ICP Mass Spectrometer (Environmental Analysis)
Agilent e-Seminar: A Metallomics Approach for Analysis of Biological and Environmental Compounds via ICP-MS | EVISA's Agenda of Events
All about Mass Spectrometry: Resources related to Mass Spectrometry | EVISA's News
Implementing Routine Elemental Speciation in Your Laboratory, in Readiness for Future Legislation | EVISA's Agenda of Events
Material database: National Institute of Standards and Technology (NIST) - SRM 955c - Toxic Elements in Caprine Blood /Level 1
Instrument database: Analytik Jena AG - PlasmaQuant® MS
Link database: iv: ICP Operations Guide
Transfer of arsenolipids from a salmon eating nursing mother to their milk | EVISA's News
Accurate determination of arsenic and its species by internal standardization for quantification by ICP-MS | EVISA's News
A short report from the speciation workshop TraceSpec 2009 | EVISA's News
Directory of scientists: Alfredo Sanz-Medel
California proposes new hexavalent chromium standard for drinking water | EVISA's News