ICP-MS

ICP-MS (Inductively Coupled Plasma Mass Spectrometry) is a type of mass spectrometry that is highly sensitive and capable of simultaneous determination of a range of elements at below one part in 1012. It is based on coupling together an inductively coupled plasma as an ion source with a mass spectrometer as a detection system for ions.
 
The ions generated within the plasma at atmospheric pressure are extracted through a series of cones into the vacuum chamber of a mass spectrometer, usually a quadrupole. Other mass analyzers coupled to ICP systems include double focusing magnetic-electric sector systems with both single and multiple collector, as well as time-of-flight (TOF) systems (both with axial and orthogonal accelerators). In any case the ions are separated on the basis of their mass-to-charge ratio and a detector receives an ion signal proportional to the concentration.
 
The concentration of a sample can be determined through calibration with elemental standards (external calibration). Accuracy and precision can be enhanced by using internal standards and rationing the measurements against these. ICP-MS also lends itself to quantitative determinations through isotope dilution analysis, a single point method based on an isotopically enriched standard.
 
 



The term "ICP-MS" was found in the following pages:

Instrument database: Thermo Elemental - X5 Quadrupole ICP-MS
Instrument database: Seiko Instruments Inc. - SPQ-6100
Toxicity and bioavailability of different selenium metabolites | EVISA's News
Instrument database: CETAC Technologies - LSX-213 Laser Ablation System
Instrument database: GBC Scientific Equipment Ltd. - OptiMass 9500 ICP-TOFMS
Brief summary: Speciation analysis for the study of metallodrugs and their biomolecular interactions | EVISA's News
Instrument database: VG Elemental - PQ 2/PQ2 Plus
Instrument database: CETAC Technologies - U-6000AT+ Ultrasonic Nebulizer/Membrane Desolvator
Directory of scientists: Maria Montes-Bayón
Component database: CPI International - ICP-MS Cones
A new concentric nebulizer for ICP sample introduction at nL-sample flow rates | EVISA's News
China: Inorganic Arsenic in Rice - An Underestimated Health Threat ? | EVISA's News
19. ICP-MS Anwendertreffen | EVISA's Agenda of Events
Directory of scientists: Alfredo Sanz-Medel
Books and Special Issues on Elemental Speciation (published since 2006) | EVISA's News
Speciation Analysis - Striving for Quality | EVISA's News
Component database: Glass Expansion - Tracey TFE - HF-resistant spray chamber for ICP-OES
Agilent Technologies publishes 2nd Edition of its Handbook of Hyphenated ICP-MS Applications | EVISA's News
Speciation analysis for cancer diagnosis | EVISA's News
Seabass populations can be differentiated by their Mercury Isotope Distribution | EVISA's News