metallodrugs

Term used to define a pharmaceutical, having a activity center containing a metal. Platinum (cisplatin, carboplatin) and gold (Auranofin) compounds are well-known in cancer therapy whereas some other gold compounds (aurithiomalate, aurothioglucose) are important antiarthritic drugs. A wide range of Tc compounds (e.g. Tc-labelled antibodies, Tc-mercaptoacetyl glycine complex) are used for diagnostic imaging of renal, cardiac and cerebral functions and of various forms of cancer. Gadolinium (III) polyaminopolycarboxylic crown complexes are widely used as contrast agents in magnetic resonance imaging.



The term "metallodrugs" was found in the following pages:

FDA investigating risk of gadolinium contrast agent brain deposits | EVISA's News
Chemical Speciation Modelling | EVISA's News
New Studies Question Safety of MRI Contrast Agents | EVISA's News
Liquid-liquid extraction in speciation analysis | EVISA's News
Themed Issue "Metallomics 2011" now available | EVISA's News
What's new ? | EVISA's News
Link database: NL: Groningen Research Institute of Pharmacy (GRIP)
Efficiency of some papillomavirus vaccines is reduced in the presence of thimerosal | EVISA's News
Directory of scientists: Chethaka Kahakachchi
Directory of scientists: Michael Sperling
Gadolinium-based contrast agents induce gadolinium deposits in cerebral vessel walls | EVISA's News
The retention of gadolinium in the human body following the use of gadolinium-based MRI contrast agents: a call to action for analytical chemists | EVISA's News
Copper molecule shows promise in fighting against cancer | EVISA's News
Chemical speciation analysis for the life sciences | EVISA's News
Journals database: Metallomics
Tracing Gadolinium-based Contrast Agents from Wastewater, via Surface Water to Drinking Water | EVISA's News
Scientific publications with participation of EVISA | EVISA's News
Books and Special Issues on Elemental Speciation (published since 2006) | EVISA's News
Speciation analysis of Gadolinium-based contrast agents using hydrophilic interaction liquid chromatography hyphenated with inductively coupled plasma-mass spectrometry by avoiding organic solvents | EVISA's News
FDA identifies no harmful effects to date with brain retention of gadolinium-based contrast agents for MRIs | EVISA's News