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Vacancy:   Pau, France: Large-scale analysis for metallophores in bacterial exudates






The post-doctoral fellow will be in charge of the method development and coordination of the acquisition and collation of mass spectrometry data for metal complexes with metallophores in bacterial exudates (strains, consortia, microcosms). He (she) will interact within an interdisciplinary consortium of a dozen of permanent researchers, other post-docs and Ph.D. students in the fields of microbiology, ecology, and molecular and cellular biology. One of his(her) tasks will be feedback and advice on the conception of the experiments to maximize the quality of the data obtained and validation of the experiments of the Ph.D. students aimed at obtaining MS data. He (she) will interact with the engineers in charge of the running and maintenance of the MS platform including 3 LC- MS Orbitrap and several LC-ICP MS systems.  
Keywords: metallomics, Fourier Transform mass spectrometry, analytical chemistry, microbiology.

Funding: E2S “Hub” MESMIC project (University of Pau) http://e2s-uppa.eu/en/index.html  
Laboratory: IPREM UMR5254 CNRS-UPPA, Pau, France. http://iprem.univ-pau.fr/fr/index.html
Applications deadline: 5 January 2019
Duration: initial appointment of 1 year extendable up to 3 years
Starting date: 15 February 2019
Teaching duties: 64 h/year
Gross salary: Monthly : 2699 € + 220 €  (teaching).

Applicant‘s profile
  • Seniority in the French public sector of less than 2 years.
  • PhD in relevant domain
  • Sound background in mass spectrometry and liquid chromatography method development is required. Elements of biostatistics and bioinformatics are a plus.
  • Fluent knowledge of English and scientific articles writing skills.
  • Good organization and communication skills
References
Flis, P., et al. (2016). Inventory of metal complexes circulating in plant fluids: a reliable method based on HPLC coupled with dual elemental and high-resolution molecular mass spectrometric detection. New Phytologist, 211(3), 1129-1141.

Ghssein, G., et al. (2016). Biosynthesis of a broad-spectrum nicotianamine-like metallophore in Staphylococcus aureus. Science, 352(6289), 1105-1109.

Walker, L. R., et al. (2017). Unambiguous identification and discovery of bacterial siderophores by direct injection 21 Tesla Fourier transform ion cyclotron resonance mass spectrometry. Metallomics, 9(1), 82-92.

Boiteau, R. M., et al.  (2016). Siderophore-based microbial adaptations to iron scarcity across the eastern Pacific Ocean. PNAS, 113(50), 14237-14242.

Deicke, M., et al. (2014). Metallophore mapping in complex matrices by metal isotope coded profiling of organic ligands. Analyst, 139(23), 6096-6099.


Contact:

Applications should be sent in a single pdf file to:

ryszard.lobinski@univ-pau.fr and simon.godin@univ-pau.fr

with the title “Post-doctoral application MESMIC”:

  • A motivation letter
  • A curriculum vitae
  • A short summary of your past research (2 pages maximum)
  • Contact details of three referees









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