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The establishment of EVISA is funded by the EU through the Fifth Framework Programme (G7RT- CT- 2002- 05112).


Supporters of EVISA includes:

Certified reference materials for mercury in biological materials



It is therefore of primary interest to have samples of human biological materials for monitoring the exposure.


The main issues to be controlled during the analysis of biological tissues for the speciation analysis of mercury are:
  • quantitativeness of extraction of the species from the tissue
  • absence of artificial formation of methylmercury during the analytical procedure
  • control of contamination mainly for inorganic mercury
  • control of the derivatization yield
  • avoidance of ion-exchange and adsorption problems on GC column packing materials
CRMs play a major role in the development and validation of methods and for quality control. The following certified reference materials (CRMs) are available for the speciation of mercury species in body fluids and tissues:
 
Supplier
Name
Material       
Certificate
IAEA
IAEA 085
Human hair
methylmercury, total Hg, Fe, Zn
IAEA IAEA 086
Human hair
methylmercury, total Hg, Fe, Zn
Immuno

Whole blood

NIES
CRM-13   
Human hair
methylmercury, total Hg, Cd, Cu, Pb, Sb, Se and Zn
NIST
SRM 966
Bovine blood
Cd, Pb, Total mercury, inorganic mercury, methylmercury
NIST
SRM 955c, level 3
Caprine blood
Cd, Pb, As, total mercury, inorganic mercury, ethylmercury, methylmercury

* () =information value only, []= original certification no longer valid
NB:! click on the material name for a link to EVISA's material database giving information on the certificate




Related EVISA Resources

Material Database: Materials related to mercury speciation
Material Database: Mercury in sediments
Material Database: Mercury in soils
Material Database: Mercury standards
Material Database: Mercury Isotopic Materials
Link Page: All about CRMs
Brief summary: Certified reference materials for mercury in marine animal tissues
Brief summary: Certified reference materials for mercury in biological materials
Brief summary: Certified Reference Materials for Speciation Analysis



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