The establishment of EVISA is funded by the EU through
the Fifth Framework Programme (G7RT- CT- 2002- 05112).
Supporters of EVISA includes:
A paramagnetic contrast agent consisting of the disodium salt of the
gadolinium ion chelated with the lipophilic moiety ethoxybenzyl (EOB)
bound to diethylenetriamine pentaacetic acid (DTPA). When placed in a
magnetic field, gadolinium produces a large magnetic moment and so a
large local magnetic field, which can enhance the relaxation rate of
nearby protons; as a result, the signal intensity of tissue images
observed with magnetic resonance imaging (MRI) may be enhanced. Because
this agent is preferentially taken up by normal functioning
hepatocytes, normal hepatic tissue is enhanced with MRI while tumor
tissue is unenhanced. In addition, because this agent is excreted in
the bile, it may be used to visualize the biliary system using MRI.