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Kusal D. Das
Professor
Environmental Health Research Unit, Department of Physiology, Al Ameen Medical College & Hospital,
Bijapur-586108, Karnataka, India
91-8352-272502 / 91-8352-208257
91-8352-272502
Kusal D. Das
kkdas@alameenmedical.org
Evaluation of heavy metal toxicity based on animal and human models:
  • Toxicity of nickel, chromium and lead and its counteraction by various chelators
  • The effect of nickel exposure in normal, protein deficient and diabetic rats explore the various alterations of intermediary metabolism and male reproductive system.
  • The role of antioxidant vitamins like L-ascorbic acid and alpha-tocopherol on heavy metal (nickel) pollution in rats has established the amelioratic effect of both the antioxidant vitamins on free radical induced oxidative stress in hemopoietic, hepatic, respiratory, renal and reproductive system of male albino rats.  
  • Effect of various nutraceuticals like Allium sativum Linn. on heavy metal [nickel and chromium (VI)] induced alteration of intermediary metabolism of normal and alloxan treated diabetic rats.
  • Oxidant-antioxidant balance, alteration of serum lipid profile, alteration of physiological homeostasis in liver, kidney, lungs and testes after exposure to nickel and chromium (VI)
  • The amelioratic effects of L-ascorbic acid, alpha-tocopherol and garlic on nickel and chromium (VI) induced oxidative stress on both normal and diabetic rats.
  • Lead acetate induced cellular hypoxia 
  • Effect of heavy metal exposure to rats in normobaric or hypobaric hypoxic condition
  • Occupational exposure of lead on human subjects and oxidative stress induced



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